1 tablet. contains 50 mg of pyridoxine. Action: Pyridoxine - Vitamin B 6 is a coenzyme of many enzymatic pathways in the body, among others, transamination and decarboxylation of amino acids.Especially important is its participation in the conversion of tryptophan, which results in serotonin and nicotinic acid. It is essential for the process of phosphorylation affects glycogenesis and glycogenolysis in muscle plays an important role in immune and hematopoietic. Reduces the secretion of prolactin. Pyridoxine deficiency symptoms are nonspecific: skin lesions, inflammation of the tongue and mucous membranes of the mouth, seizures, anemia, microcytic or hypochromic megaloblastic, neuritis, depression. Its absence may contribute to the development of kidney oxalate.Pyridoxine is well absorbed from the gastrointestinal tract. Excreted in the urine. Excreted in human milk. Indications: hypovitaminosis B 6 , akrodynia, radiation sickness, anemia macro- and Microcytic, leukopenia, diseases of the peripheral and central nervous system, muscular dystrophy, inflammation of the oral mucosa, paradontopatie, seborrhea, exfoliative erythroderma, sunburn, homocystinuria, hyperoxaluria, premenstrual syndrome, the use of hormonal contraceptives, nausea in pregnant women, treatment with isoniazid, hyperkinetic syndrome in children, malabsorption, alcoholism. undesirable effects: During prolonged high doses - peripheral neuropathy. Interaction: Action antagonistic levodopa . When applying to amiodarone - photosensitization. Hormonal contraceptives, hydralazine, penicillamine increase the need for pyridoxine. Reduces the neurotoxic effects of isoniazid. Dosage: Adults 0.05-0.1 g orally 3 times a day; prevention of complications neurotoxic effects of isoniazid-treated - 0.05 g once a day; preventing the sunburn - 0.15-0.2 g once or within 10 hours after 0.05-0.1 g / dose at 1 hour; preventing leukopenia - 0.05 g once a day; in radiation sickness, nausea in pregnant - 0.05-0.1 g once a day; in cystinuria - 0.05-0.15 g three times per day (up to 0.6 g per day). Children from 2 months of age 0,025-0,15 g per day orally in two doses (in homocystinuria to 0.45 g per day).